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Amylin/leptin synergy is absent in extreme obesity and not restored by calorie restriction‐induced weight loss in rats

OBJECTIVE: Co‐administration of amylin and leptin induces synergistic and clinically meaningful (>10%) weight loss that is attenuated as the degree of obesity increases. We explored whether calorie restriction (CR) could restore amylin/leptin synergy in very obese rats. METHODS: Sprague Dawley ra...

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Detalles Bibliográficos
Autores principales:	Trevaskis, J. L., Wittmer, C., Athanacio, J., Griffin, P. S., Parkes, D. G., Roth, J. D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192543/ https://www.ncbi.nlm.nih.gov/pubmed/28090343 http://dx.doi.org/10.1002/osp4.62

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