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Biliary atresia: Where do we stand now?

The pathway from clinical suspicion to establishing the diagnosis of biliary atresia in a child with jaundice is a daunting task. However, investigations available help to point towards the correct diagnosis in reasonable time frame. Imaging by Sonography has identified several parameters which can...

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Autor principal: Govindarajan, Krishna Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192550/
https://www.ncbi.nlm.nih.gov/pubmed/28083081
http://dx.doi.org/10.4254/wjh.v8.i36.1593
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author Govindarajan, Krishna Kumar
author_facet Govindarajan, Krishna Kumar
author_sort Govindarajan, Krishna Kumar
collection PubMed
description The pathway from clinical suspicion to establishing the diagnosis of biliary atresia in a child with jaundice is a daunting task. However, investigations available help to point towards the correct diagnosis in reasonable time frame. Imaging by Sonography has identified several parameters which can be of utility in the diagnostic work up. Comparison of Sonography with imaging by Nuclear medicine can bring out the significant differences and also help in appropriate imaging. The battery of Biochemical tests, available currently, enable better understanding of the line-up of investigations in a given child with neonatal cholestasis. Management protocols enable standardized care with optimal outcome. The place of surgical management in biliary atresia is undisputed, although Kasai procedure and primary liver transplantation have been pitted against each other. This article functions as a platform to bring forth the various dimensions of biliary atresia.
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spelling pubmed-51925502017-01-12 Biliary atresia: Where do we stand now? Govindarajan, Krishna Kumar World J Hepatol Review The pathway from clinical suspicion to establishing the diagnosis of biliary atresia in a child with jaundice is a daunting task. However, investigations available help to point towards the correct diagnosis in reasonable time frame. Imaging by Sonography has identified several parameters which can be of utility in the diagnostic work up. Comparison of Sonography with imaging by Nuclear medicine can bring out the significant differences and also help in appropriate imaging. The battery of Biochemical tests, available currently, enable better understanding of the line-up of investigations in a given child with neonatal cholestasis. Management protocols enable standardized care with optimal outcome. The place of surgical management in biliary atresia is undisputed, although Kasai procedure and primary liver transplantation have been pitted against each other. This article functions as a platform to bring forth the various dimensions of biliary atresia. Baishideng Publishing Group Inc 2016-12-28 2016-12-28 /pmc/articles/PMC5192550/ /pubmed/28083081 http://dx.doi.org/10.4254/wjh.v8.i36.1593 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Review
Govindarajan, Krishna Kumar
Biliary atresia: Where do we stand now?
title Biliary atresia: Where do we stand now?
title_full Biliary atresia: Where do we stand now?
title_fullStr Biliary atresia: Where do we stand now?
title_full_unstemmed Biliary atresia: Where do we stand now?
title_short Biliary atresia: Where do we stand now?
title_sort biliary atresia: where do we stand now?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192550/
https://www.ncbi.nlm.nih.gov/pubmed/28083081
http://dx.doi.org/10.4254/wjh.v8.i36.1593
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