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CML/RAGE signal induces calcification cascade in diabetes
OBJECTIVE: Vascular calcification is a significant predictor of coronary heart disease events, stroke, and lower-limb amputation. Advanced glycation end-products (AGEs) play a key role in the development of vascular calcification. However, the role of Nε-carboxymethyl-lysine (CML), a major active in...
Autores principales: | Wang, Zhongqun, Li, Lihua, Du, Rui, Yan, Jinchuan, Liu, Naifeng, Yuan, Wei, Jiang, Yicheng, Xu, Suining, Ye, Fei, Yuan, Guoyue, Zhang, Baohai, Liu, Peijing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192585/ https://www.ncbi.nlm.nih.gov/pubmed/28035243 http://dx.doi.org/10.1186/s13098-016-0196-7 |
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