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Small interfering RNA targeting NF-κB attenuates lipopolysaccharide-induced acute lung injury in rats

BACKGROUND: To investigate the anti-inflammatory effects of specific small interfering RNA targeting NF-κB on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in rats. METHOD: Acute lung injury was induced in Sprague-Dawley rats by intraperitoneal injection with LPS (5 mg/kg), followed by im...

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Detalles Bibliográficos
Autores principales: Li, Ning, Song, Yuanbin, Zhao, Wei, Han, Tingting, Lin, Shuhui, Ramirez, Oscar, Liang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192588/
https://www.ncbi.nlm.nih.gov/pubmed/28031043
http://dx.doi.org/10.1186/s12899-016-0027-y