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Small interfering RNA targeting NF-κB attenuates lipopolysaccharide-induced acute lung injury in rats
BACKGROUND: To investigate the anti-inflammatory effects of specific small interfering RNA targeting NF-κB on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in rats. METHOD: Acute lung injury was induced in Sprague-Dawley rats by intraperitoneal injection with LPS (5 mg/kg), followed by im...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192588/ https://www.ncbi.nlm.nih.gov/pubmed/28031043 http://dx.doi.org/10.1186/s12899-016-0027-y |