Distinct roles of immunoreceptor tyrosine‐based motifs in immunosuppressive indoleamine 2,3‐dioxygenase 1

The enzyme indoleamine 2,3‐dioxygenase 1 (IDO1) catalyses the initial, rate‐limiting step in tryptophan (Trp) degradation, resulting in tryptophan starvation and the production of immunoregulatory kynurenines. IDO1's catalytic function has long been considered as the one mechanism responsible f...

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Detalles Bibliográficos
Autores principales: Albini, Elisa, Rosini, Verdiana, Gargaro, Marco, Mondanelli, Giada, Belladonna, Maria L., Pallotta, Maria Teresa, Volpi, Claudia, Fallarino, Francesca, Macchiarulo, Antonio, Antognelli, Cinzia, Bianchi, Roberta, Vacca, Carmine, Puccetti, Paolo, Grohmann, Ursula, Orabona, Ciriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192792/
https://www.ncbi.nlm.nih.gov/pubmed/27696702
http://dx.doi.org/10.1111/jcmm.12954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192792/
https://www.ncbi.nlm.nih.gov/pubmed/27696702
http://dx.doi.org/10.1111/jcmm.12954

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