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Structural basis for decreased induction of class IB PI3‐kinases expression by MIF inhibitors

Macrophage migration inhibitory factor (MIF) is a master regulator of proinflammatory cytokines and plays pathological roles when not properly regulated in rheumatoid arthritis, lupus, atherosclerosis, asthma and cancer. Unlike canonical cytokines, MIF has vestigial keto‐enol tautomerase activity. M...

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Detalles Bibliográficos
Autores principales: Singh, Abhay Kumar, Pantouris, Georgios, Borosch, Sebastian, Rojanasthien, Siripong, Cho, Thomas Yoonsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192866/
https://www.ncbi.nlm.nih.gov/pubmed/27619729
http://dx.doi.org/10.1111/jcmm.12949

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