Cargando…
Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity
Natural killer (NK) cells are essential for killing transformed and virally infected cells. To prevent auto-reactivity, NK cell activation is inhibited by inhibitory receptors that activate the tyrosine phosphatase SHP-1, which dephosphorylates signaling molecules crucial for NK cell activation. Ini...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193043/ https://www.ncbi.nlm.nih.gov/pubmed/28042374 http://dx.doi.org/10.1080/19420889.2016.1216739 |