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Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity
Natural killer (NK) cells are essential for killing transformed and virally infected cells. To prevent auto-reactivity, NK cell activation is inhibited by inhibitory receptors that activate the tyrosine phosphatase SHP-1, which dephosphorylates signaling molecules crucial for NK cell activation. Ini...
Autores principales: | Matalon, Omri, Barda-Saad, Mira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193043/ https://www.ncbi.nlm.nih.gov/pubmed/28042374 http://dx.doi.org/10.1080/19420889.2016.1216739 |
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