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Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects
Grasping relies on a network of parieto-frontal areas lying on the dorsolateral and dorsomedial parts of the hemispheres. However, the initiation and sequencing of voluntary actions also requires the contribution of mesial premotor regions, particularly the pre-supplementary motor area F6. We record...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193144/ https://www.ncbi.nlm.nih.gov/pubmed/27733538 http://dx.doi.org/10.1093/cercor/bhw315 |
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author | Lanzilotto, Marco Livi, Alessandro Maranesi, Monica Gerbella, Marzio Barz, Falk Ruther, Patrick Fogassi, Leonardo Rizzolatti, Giacomo Bonini, Luca |
author_facet | Lanzilotto, Marco Livi, Alessandro Maranesi, Monica Gerbella, Marzio Barz, Falk Ruther, Patrick Fogassi, Leonardo Rizzolatti, Giacomo Bonini, Luca |
author_sort | Lanzilotto, Marco |
collection | PubMed |
description | Grasping relies on a network of parieto-frontal areas lying on the dorsolateral and dorsomedial parts of the hemispheres. However, the initiation and sequencing of voluntary actions also requires the contribution of mesial premotor regions, particularly the pre-supplementary motor area F6. We recorded 233 F6 neurons from 2 monkeys with chronic linear multishank neural probes during reaching–grasping visuomotor tasks. We showed that F6 neurons play a role in the control of forelimb movements and some of them (26%) exhibit visual and/or motor specificity for the target object. Interestingly, area F6 neurons form 2 functionally distinct populations, showing either visually-triggered or movement-related bursts of activity, in contrast to the sustained visual-to-motor activity displayed by ventral premotor area F5 neurons recorded in the same animals and with the same task during previous studies. These findings suggest that F6 plays a role in object grasping and extend existing models of the cortical grasping network. |
format | Online Article Text |
id | pubmed-5193144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-51931442017-01-04 Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects Lanzilotto, Marco Livi, Alessandro Maranesi, Monica Gerbella, Marzio Barz, Falk Ruther, Patrick Fogassi, Leonardo Rizzolatti, Giacomo Bonini, Luca Cereb Cortex Original Articles Grasping relies on a network of parieto-frontal areas lying on the dorsolateral and dorsomedial parts of the hemispheres. However, the initiation and sequencing of voluntary actions also requires the contribution of mesial premotor regions, particularly the pre-supplementary motor area F6. We recorded 233 F6 neurons from 2 monkeys with chronic linear multishank neural probes during reaching–grasping visuomotor tasks. We showed that F6 neurons play a role in the control of forelimb movements and some of them (26%) exhibit visual and/or motor specificity for the target object. Interestingly, area F6 neurons form 2 functionally distinct populations, showing either visually-triggered or movement-related bursts of activity, in contrast to the sustained visual-to-motor activity displayed by ventral premotor area F5 neurons recorded in the same animals and with the same task during previous studies. These findings suggest that F6 plays a role in object grasping and extend existing models of the cortical grasping network. Oxford University Press 2016-12 2016-12-26 /pmc/articles/PMC5193144/ /pubmed/27733538 http://dx.doi.org/10.1093/cercor/bhw315 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Articles Lanzilotto, Marco Livi, Alessandro Maranesi, Monica Gerbella, Marzio Barz, Falk Ruther, Patrick Fogassi, Leonardo Rizzolatti, Giacomo Bonini, Luca Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects |
title | Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects |
title_full | Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects |
title_fullStr | Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects |
title_full_unstemmed | Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects |
title_short | Extending the Cortical Grasping Network: Pre-supplementary Motor Neuron Activity During Vision and Grasping of Objects |
title_sort | extending the cortical grasping network: pre-supplementary motor neuron activity during vision and grasping of objects |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193144/ https://www.ncbi.nlm.nih.gov/pubmed/27733538 http://dx.doi.org/10.1093/cercor/bhw315 |
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