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Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma

BACKGROUND: Surgical excision is the treatment of choice for basal cell carcinoma and micrographic surgery considered the gold standard, however not yet used routinely worldwide available, as in Brazil. Considering this, a previously developed treatment guideline, which the majority of tumors were t...

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Autores principales: Luz, Flávio Barbosa, Ferron, Camila, Cardoso, Gilberto Perez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193181/
https://www.ncbi.nlm.nih.gov/pubmed/28099591
http://dx.doi.org/10.1590/abd1806-4841.20165919
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author Luz, Flávio Barbosa
Ferron, Camila
Cardoso, Gilberto Perez
author_facet Luz, Flávio Barbosa
Ferron, Camila
Cardoso, Gilberto Perez
author_sort Luz, Flávio Barbosa
collection PubMed
description BACKGROUND: Surgical excision is the treatment of choice for basal cell carcinoma and micrographic surgery considered the gold standard, however not yet used routinely worldwide available, as in Brazil. Considering this, a previously developed treatment guideline, which the majority of tumors were treated by conventional technique (not micrographic) was tested. OBJECTIVE: To establish the recurrence rate of basal cell carcinomas treated according to this guideline. METHOD: Between May 2001 and July 2012, 919 basal cell carcinoma lesions in 410 patients were treated according to the proposed guideline. Patients were followed-up and reviewed between September 2013 and February 2014 for clinical, dermatoscopic and histopathologic detection of possible recurrences. RESULTS: After application of exclusion criteria, 520 lesions were studied, with 88.3% primary and 11.7% recurrent tumors. Histological pattern was indolent in 85.5%, 48.6% were located in high risk areas and 70% small tumors. Only 7.3% were treated by Mohs micrographic surgery. The recurrence rate, in an average follow-up period of 4.37 years, was 1.3% for primary and 1.63% for recurrent tumors. Study limitations: unicenter study, with all patients operated on by the same surgeon. CONCLUSION: The treatment guideline utilized seems a helpful guide for surgical treatment of basal cell carcinoma, especially if micrographic surgery is not available.
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spelling pubmed-51931812016-12-29 Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma Luz, Flávio Barbosa Ferron, Camila Cardoso, Gilberto Perez An Bras Dermatol Investigation BACKGROUND: Surgical excision is the treatment of choice for basal cell carcinoma and micrographic surgery considered the gold standard, however not yet used routinely worldwide available, as in Brazil. Considering this, a previously developed treatment guideline, which the majority of tumors were treated by conventional technique (not micrographic) was tested. OBJECTIVE: To establish the recurrence rate of basal cell carcinomas treated according to this guideline. METHOD: Between May 2001 and July 2012, 919 basal cell carcinoma lesions in 410 patients were treated according to the proposed guideline. Patients were followed-up and reviewed between September 2013 and February 2014 for clinical, dermatoscopic and histopathologic detection of possible recurrences. RESULTS: After application of exclusion criteria, 520 lesions were studied, with 88.3% primary and 11.7% recurrent tumors. Histological pattern was indolent in 85.5%, 48.6% were located in high risk areas and 70% small tumors. Only 7.3% were treated by Mohs micrographic surgery. The recurrence rate, in an average follow-up period of 4.37 years, was 1.3% for primary and 1.63% for recurrent tumors. Study limitations: unicenter study, with all patients operated on by the same surgeon. CONCLUSION: The treatment guideline utilized seems a helpful guide for surgical treatment of basal cell carcinoma, especially if micrographic surgery is not available. Sociedade Brasileira de Dermatologia 2016 /pmc/articles/PMC5193181/ /pubmed/28099591 http://dx.doi.org/10.1590/abd1806-4841.20165919 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Investigation
Luz, Flávio Barbosa
Ferron, Camila
Cardoso, Gilberto Perez
Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
title Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
title_full Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
title_fullStr Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
title_full_unstemmed Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
title_short Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
title_sort analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193181/
https://www.ncbi.nlm.nih.gov/pubmed/28099591
http://dx.doi.org/10.1590/abd1806-4841.20165919
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