Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor

Dysfunction of the melanocortin system can result in severe obesity accompanied with dyslipidemia and symptoms of the metabolic syndrome but the effect on vascular atherogenesis is not known. To study the impact of obesity and dyslipidemia on the cardiovascular system, we generated mice double-defic...

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Detalles Bibliográficos
Autores principales: Lede, Vera, Franke, Christin, Meusel, Andrej, Teupser, Daniel, Ricken, Albert, Thiery, Joachim, Schiller, Jürgen, Huster, Daniel, Schöneberg, Torsten, Schulz, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193345/
https://www.ncbi.nlm.nih.gov/pubmed/28030540
http://dx.doi.org/10.1371/journal.pone.0167888

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