Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions

The Hedgehog pathway is a potent regulator of cellular growth and plays a central role in the development of many cancers including basal cell carcinoma (BCC). The majority of BCCs arise from mutations in the Patched receptor resulting in constitutive activation of the Hedgehog pathway. Secondary dr...

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Detalles Bibliográficos
Autores principales: Urman, Nicole M., Mirza, Amar, Atwood, Scott X., Whitson, Ramon J., Sarin, Kavita Y., Tang, Jean Y., Oro, Anthony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193403/
https://www.ncbi.nlm.nih.gov/pubmed/28030567
http://dx.doi.org/10.1371/journal.pone.0168031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193403/
https://www.ncbi.nlm.nih.gov/pubmed/28030567
http://dx.doi.org/10.1371/journal.pone.0168031

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