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Heterogeneous Niche Activity of Ex-Vivo Expanded MSCs as Factor for Variable Outcomes in Hematopoietic Recovery

Ex-vivo expanded mesenchymal stromal cells (MSCs) are increasingly used for paracrine support of hematopoietic stem cell (HSC) regeneration, but inconsistent outcomes have hindered ongoing clinical trials. Here, we show that significant heterogeneity in the niche activity of MSCs is created during t...

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Detalles Bibliográficos
Autores principales:	Kim, Jung-Ho, Lee, Ho-Sun, Choi, Hyun-Kyung, Kim, Jin-A, Chu, In-Sun, Leem, Sun-Hee, Oh, Il-Hoan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193420/ https://www.ncbi.nlm.nih.gov/pubmed/28030562 http://dx.doi.org/10.1371/journal.pone.0168036

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