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Human Lin28 Forms a High-Affinity 1:1 Complex with the 106~363 Cluster miRNA miR-363
[Image: see text] Lin28A is a post-transcriptional regulator of gene expression that interacts with and negatively regulates the biogenesis of let-7 family miRNAs. Recent data suggested that Lin28A also binds the putative tumor suppressor miR-363, a member of the 106~363 cluster of miRNAs. Affinity...
Autores principales: | Peters, Daniel T., Fung, Herman K. H., Levdikov, Vladimir M., Irmscher, Tobias, Warrander, Fiona C., Greive, Sandra J., Kovalevskiy, Oleg, Isaacs, Harry V., Coles, Mark, Antson, Alfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193468/ https://www.ncbi.nlm.nih.gov/pubmed/27559824 http://dx.doi.org/10.1021/acs.biochem.6b00682 |
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