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Knock out of the NADPH oxidase Nox4 has no impact on life span in mice
The free radical theory of aging suggests reactive oxygen species as a main reason for accumulation of damage events eventually leading to aging. Nox4, a member of the family of NADPH oxidases constitutively produces ROS and therefore has the potential to be a main driver of aging. Herein we analyze...
Autores principales: | Rezende, Flavia, Schürmann, Christoph, Schütz, Susanne, Harenkamp, Sabine, Herrmann, Eva, Seimetz, Michael, Weißmann, Norbert, Schröder, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196091/ https://www.ncbi.nlm.nih.gov/pubmed/28038425 http://dx.doi.org/10.1016/j.redox.2016.12.012 |
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