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The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
Various steady state and inflamed tissues have been shown to contain a heterogeneous DC population consisting of developmentally distinct subsets, including cDC1s, cDC2s and monocyte-derived DCs, displaying differential functional specializations. The identification of functionally distinct tumour-a...
Autores principales: | Laoui, Damya, Keirsse, Jiri, Morias, Yannick, Van Overmeire, Eva, Geeraerts, Xenia, Elkrim, Yvon, Kiss, Mate, Bolli, Evangelia, Lahmar, Qods, Sichien, Dorine, Serneels, Jens, Scott, Charlotte L., Boon, Louis, De Baetselier, Patrick, Mazzone, Massimiliano, Guilliams, Martin, Van Ginderachter, Jo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196231/ https://www.ncbi.nlm.nih.gov/pubmed/28008905 http://dx.doi.org/10.1038/ncomms13720 |
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