Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction

Mutations affecting the apoptosis-inducing function of the Fas/CD95 TNF-family receptor result in autoimmune and lymphoproliferative disease. However, Fas can also costimulate T-cell activation and promote tumour cell growth and metastasis. Palmitoylation at a membrane proximal cysteine residue enab...

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Detalles Bibliográficos
Autores principales: Cruz, Anthony C., Ramaswamy, Madhu, Ouyang, Claudia, Klebanoff, Christopher A., Sengupta, Prabuddha, Yamamoto, Tori N., Meylan, Françoise, Thomas, Stacy K., Richoz, Nathan, Eil, Robert, Price, Susan, Casellas, Rafael, Rao, V. Koneti, Lippincott-Schwartz, Jennifer, Restifo, Nicholas P., Siegel, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196435/
https://www.ncbi.nlm.nih.gov/pubmed/28008916
http://dx.doi.org/10.1038/ncomms13895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196435/
https://www.ncbi.nlm.nih.gov/pubmed/28008916
http://dx.doi.org/10.1038/ncomms13895

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