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Reprogramming the immunological microenvironment through radiation and targeting Axl

Increasing evidence suggests that ionizing radiation therapy (RT) in combination with checkpoint immunotherapy is highly effective in treating a subset of cancers. To better understand the limited responses to this combination we analysed the genetic, microenvironmental, and immune factors in tumour...

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Detalles Bibliográficos
Autores principales: Aguilera, Todd A., Rafat, Marjan, Castellini, Laura, Shehade, Hussein, Kariolis, Mihalis S., Hui, Angela Bik-Yu, Stehr, Henning, von Eyben, Rie, Jiang, Dadi, Ellies, Lesley G., Koong, Albert C., Diehn, Maximilian, Rankin, Erinn B., Graves, Edward E., Giaccia, Amato J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196438/
https://www.ncbi.nlm.nih.gov/pubmed/28008921
http://dx.doi.org/10.1038/ncomms13898