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Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist

The diversity and uniqueness of flatworm G protein coupled receptors (GPCRs) provides impetus for identifying ligands useful as tools for studying flatworm biology, or as therapeutics for treating diseases caused by parasitic flatworm infections. To catalyse this discovery process, technologies opti...

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Detalles Bibliográficos
Autores principales: Chan, John D., Grab, Thomas, Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196488/
https://www.ncbi.nlm.nih.gov/pubmed/27397764
http://dx.doi.org/10.1016/j.ijpddr.2016.06.002

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