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Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal drug. Flubendazole (FLBZ), a benzimidazole an...

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Detalles Bibliográficos
Autores principales:	O'Neill, Maeghan, Ballesteros, Cristina, Tritten, Lucienne, Burkman, Erica, Zaky, Weam I., Xia, Jianguo, Moorhead, Andrew, Williams, Steven A., Geary, Timothy G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance II", pp. 288 - 370,
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196492/ https://www.ncbi.nlm.nih.gov/pubmed/27733308 http://dx.doi.org/10.1016/j.ijpddr.2016.09.005

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