Cargando…

Preventing Radiobleaching of Cyanine Fluorophores Enhances Stability of Nuclear/NIRF Multimodality Imaging Agents

Despite the large interest in nuclear/optical multimodality imaging, the effect of radiation on the fluorescence of fluorophores remains largely unexplored. Herein, we report on the radiobleaching of cyanine fluorophores and describe conditions to provide robust radioprotection under practical (pre)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hernandez, Reinier, Heskamp, Sandra, Rijpkema, Mark, Bos, Desirée L., Goldenberg, David M., McBride, William J., Morgenstern, Alfred, Bruchertseifer, Frank, Cai, Weibo, Boerman, Otto C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Short Research Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196880/ https://www.ncbi.nlm.nih.gov/pubmed/28042311 http://dx.doi.org/10.7150/thno.15124

Ejemplares similares

NIRF Heptamethine Cyanine Dye Nanocomplexes for Multi Modal Theranosis of Tumors
por: Thomas, Reju George, et al.
Publicado: (2017)

A pretargeted multimodal approach for image-guided resection in a xenograft model of colorectal cancer
por: Elekonawo, Fortuné M. K., et al.
Publicado: (2019)

Carcinoembryonic antigen-targeted photodynamic therapy in colorectal cancer models
por: Elekonawo, Fortuné M. K., et al.
Publicado: (2019)

Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging
por: Bai, Lang, et al.
Publicado: (2022)

A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer
por: Adumeau, Pierre, et al.
Publicado: (2016)

Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA
por: Liu, Yijin, et al.
Publicado: (2017)

(89)Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art (89)Zr Radiochemistry
por: Heskamp, Sandra, et al.
Publicado: (2017)

Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope
por: Shrivastav, Manisha, et al.
Publicado: (2018)

CD146-targeted immunoPET and NIRF Imaging of Hepatocellular Carcinoma with a Dual-Labeled Monoclonal Antibody
por: Hernandez, Reinier, et al.
Publicado: (2016)

Fluorophore-conjugated 4-1BB antibody enables early detection of T-cell responses in inflammatory arthritis via NIRF imaging
por: Duan, Shao, et al.
Publicado: (2022)

Correction: Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope
por: Shrivastav, Manisha, et al.
Publicado: (2019)

Albumin-chaperoned cyanine dye yields superbright NIR-II fluorophore with enhanced pharmacokinetics
por: Tian, Rui, et al.
Publicado: (2019)

Molecular and Spectroscopic Characterization of Green and Red Cyanine Fluorophores from the Alexa Fluor and AF Series
por: Gebhardt, Christian, et al.
Publicado: (2021)

Development and characterization of a theranostic multimodal anti-PSMA targeting agent for imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing tumors
por: Lütje, Susanne, et al.
Publicado: (2019)

Electrophile-Integrating Smiles Rearrangement Provides Previously Inaccessible C4′-O-Alkyl Heptamethine Cyanine Fluorophores
por: Nani, Roger R., et al.
Publicado: (2015)

Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma
por: Odenthal, Julia, et al.
Publicado: (2018)

Novel Peptide NIRF Optical Surgical Navigation Agents for HNSCC
por: Ding, Haiming, et al.
Publicado: (2019)

Carbonic Anhydrase IX-Targeted α-Radionuclide Therapy with 225Ac Inhibits Tumor Growth in a Renal Cell Carcinoma Model
por: Merkx, Robin I. J., et al.
Publicado: (2022)

In Vivo Tumor Vasculature Targeted PET/NIRF Imaging with TRC105(Fab)-Conjugated, Dual-Labeled Mesoporous Silica Nanoparticles
por: Chen, Feng, et al.
Publicado: (2014)

Ex Vivo Assessment of Tumor-Targeting Fluorescent Tracers for Image-Guided Surgery
por: Elekonawo, Fortuné M.K., et al.
Publicado: (2020)

PSMA-targeting agents for radio- and fluorescence-guided prostate cancer surgery
por: Derks, Yvonne H.W., et al.
Publicado: (2019)

Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging
por: Stammes, Marieke A., et al.
Publicado: (2016)

Near Infrared Fluorescence (NIRF) Molecular Imaging of Oxidized LDL with an Autoantibody in Experimental Atherosclerosis
por: Khamis, Ramzi Y, et al.
Publicado: (2016)

Long-term prevalence of NIRF-labeled magnetic nanoparticles for the diagnostic and intraoperative imaging of inflammation
por: Domey, Jenny, et al.
Publicado: (2016)

Challenges in Tracking of Fluorochrome-Labelled Nanoparticles in Mice via Whole Body NIRF Imaging
por: Gaffron, Florian, et al.
Publicado: (2020)

Photoswitching Mechanism of Cyanine Dyes
por: Dempsey, Graham T., et al.
Publicado: (2009)

Cyanine conjugates in cancer theranostics
por: Li, Yang, et al.
Publicado: (2020)

Magnetic Mesoporous Silica Nanorods Loaded with Ceria and Functionalized with Fluorophores for Multimodal Imaging
por: Grzelak, Jan, et al.
Publicado: (2022)

PSMA Ligands for Radionuclide Imaging and Therapy of Prostate Cancer: Clinical Status
por: Lütje, Susanne, et al.
Publicado: (2015)

Bio-functionalized dense-silica nanoparticles for MR/NIRF imaging of CD146 in gastric cancer
por: Wang, Pu, et al.
Publicado: (2015)

NIRF Optical/PET Dual-Modal Imaging of Hepatocellular Carcinoma Using Heptamethine Carbocyanine Dye
por: Zhang, Caiqin, et al.
Publicado: (2018)

Dual-Mode Contrast Agents with RGD-Modified Polymer for Tumour-Targeted US/NIRF Imaging
por: Nie, Zhenhui, et al.
Publicado: (2020)

NIRF guided robot-assisted diverticulectomy and ureteral reimplantation for bladder cancer within Hutch diverticulum
por: Carbonara, Umberto, et al.
Publicado: (2021)

Near-Infrared Heptamethine Cyanine Based Iron Oxide Nanoparticles for Tumor Targeted Multimodal Imaging and Photothermal Therapy
por: Lee, Sejy, et al.
Publicado: (2017)

Hybrid Multimodal Imaging Synthons for Chemoselective and Efficient Biomolecule Modification with Chelator and Near-Infrared Fluorescent Cyanine Dye
por: Hübner, Ralph, et al.
Publicado: (2020)

A Cyanine‐Bridged Somatostatin Hybrid Probe for Multimodal SSTR2 Imaging in Vitro and in Vivo: Synthesis and Evaluation
por: Heing‐Becker, Isabelle, et al.
Publicado: (2021)

Supply and Clinical Application of Actinium-225 and Bismuth-213
por: Morgenstern, Alfred, et al.
Publicado: (2020)

Cyanine Dye–Nucleic Acid Interactions
por: Armitage, Bruce A.
Publicado: (2008)

Multimodal CEA-targeted fluorescence and radioguided cytoreductive surgery for peritoneal metastases of colorectal origin
por: de Gooyer, Jan Marie, et al.
Publicado: (2022)

SPECT/NIRF Dual Modality Imaging for Detection of Intraperitoneal Colon Tumor with an Avidin/Biotin Pretargeting System
por: Dong, Chengyan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_j20fn9d5oj24i80ls8efurfav6