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Microbubble gas volume: A unifying dose parameter in blood-brain barrier opening by focused ultrasound

Focused ultrasound with microbubbles is being developed to transiently, locally and noninvasively open the blood-brain barrier (BBB) for improved pharmaceutical delivery. Prior work has demonstrated that, for a given concentration dose, microbubble size affects both the intravascular circulation per...

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Detalles Bibliográficos
Autores principales: Song, Kang-Ho, Fan, Alexander C., Hinkle, Joshua J., Newman, Joshua, Borden, Mark A., Harvey, Brandon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196892/
https://www.ncbi.nlm.nih.gov/pubmed/28042323
http://dx.doi.org/10.7150/thno.15987