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The Emergence of Pan-Cancer CIMP and Its Elusive Interpretation

Epigenetic dysregulation is recognized as a hallmark of cancer. In the last 16 years, a CpG island methylator phenotype (CIMP) has been documented in tumors originating from different tissues. However, a looming question in the field is whether or not CIMP is a pan-cancer phenomenon or a tissue-spec...

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Detalles Bibliográficos
Autores principales:	Miller, Brendan F., Sánchez-Vega, Francisco, Elnitski, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197955/ https://www.ncbi.nlm.nih.gov/pubmed/27879658 http://dx.doi.org/10.3390/biom6040045

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