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Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221

Bufalin, a major component of the Chinese medicine ChanSu, which is prepared from the skin and parotid venom glands of toads, has shown cytotoxicity in several malignant tumors. Here, we reported that bufalin inhibited proliferation and induced mitochondria-dependent apoptosis in U-2OS and Saos-2 os...

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Detalles Bibliográficos
Autores principales: Zhang, Jianjun, Sha, Jingjing, Zhou, Yan, Han, Kun, Wang, Yaling, Su, Yang, Yin, Xiuyi, Hu, Haiyan, Yao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198087/
https://www.ncbi.nlm.nih.gov/pubmed/28074104
http://dx.doi.org/10.1155/2016/7319464