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Varicella-Zoster Virus Infectious Cycle: ER Stress, Autophagic Flux, and Amphisome-Mediated Trafficking

Varicella-zoster virus (VZV) induces abundant autophagy. Of the nine human herpesviruses, the VZV genome is the smallest (~124 kbp), lacking any known inhibitors of autophagy, such as the herpes simplex virus ICP34.5 neurovirulence gene. Therefore, this review assesses the evidence for VZV-induced c...

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Detalles Bibliográficos
Autores principales: Grose, Charles, Buckingham, Erin M., Carpenter, John E., Kunkel, Jeremy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198167/
https://www.ncbi.nlm.nih.gov/pubmed/27973418
http://dx.doi.org/10.3390/pathogens5040067