SecA—a New Twist in the Tale

A paper published in this issue of the Journal of Bacteriology (D. Huber, M. Jamshad, R. Hanmer, D. Schibich, K. Döring, I. Marcomini, G. Kramer, and B. Bukau, J Bacteriol 199:e0622-16, 2017, https://doi.org/10.1128/JB.00622-16) provides us with a timely reminder that all is not as clear as we had p...

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Detalles Bibliográficos
Autor principal: Collinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198485/
https://www.ncbi.nlm.nih.gov/pubmed/27799326
http://dx.doi.org/10.1128/JB.00736-16
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author Collinson, Ian
author_facet Collinson, Ian
author_sort Collinson, Ian
collection PubMed
description A paper published in this issue of the Journal of Bacteriology (D. Huber, M. Jamshad, R. Hanmer, D. Schibich, K. Döring, I. Marcomini, G. Kramer, and B. Bukau, J Bacteriol 199:e0622-16, 2017, https://doi.org/10.1128/JB.00622-16) provides us with a timely reminder that all is not as clear as we had previously thought in the general bacterial secretion system. The paper describes a new mode of secretion through the Sec system—“uncoupled cotranslocation”—for the passage of proteins across the bacterial inner membrane and suggests that we might rethink the nature and mechanism of the targeting and transport steps toward protein export.
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spelling pubmed-51984852017-01-09 SecA—a New Twist in the Tale Collinson, Ian J Bacteriol Commentary A paper published in this issue of the Journal of Bacteriology (D. Huber, M. Jamshad, R. Hanmer, D. Schibich, K. Döring, I. Marcomini, G. Kramer, and B. Bukau, J Bacteriol 199:e0622-16, 2017, https://doi.org/10.1128/JB.00622-16) provides us with a timely reminder that all is not as clear as we had previously thought in the general bacterial secretion system. The paper describes a new mode of secretion through the Sec system—“uncoupled cotranslocation”—for the passage of proteins across the bacterial inner membrane and suggests that we might rethink the nature and mechanism of the targeting and transport steps toward protein export. American Society for Microbiology 2016-12-28 /pmc/articles/PMC5198485/ /pubmed/27799326 http://dx.doi.org/10.1128/JB.00736-16 Text en Copyright © 2016 Collinson. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Collinson, Ian
SecA—a New Twist in the Tale
title SecA—a New Twist in the Tale
title_full SecA—a New Twist in the Tale
title_fullStr SecA—a New Twist in the Tale
title_full_unstemmed SecA—a New Twist in the Tale
title_short SecA—a New Twist in the Tale
title_sort seca—a new twist in the tale
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198485/
https://www.ncbi.nlm.nih.gov/pubmed/27799326
http://dx.doi.org/10.1128/JB.00736-16
work_keys_str_mv AT collinsonian secaanewtwistinthetale

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