Neuroendocrine prostate cancer (NEPCa) increased the neighboring PCa chemo-resistance via altering the PTHrP/p38/Hsp27/androgen receptor (AR)/p21 signals

Prostatic neuroendocrine cells (NE) are an integral part of prostate cancer (PCa) that are associated with PCa progression. As the current androgen-deprivation therapy (ADT) with anti-androgens may promote the neuroendocrine PCa (NEPCa) development, and few therapies can effectively suppress NEPCa,...

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Detalles Bibliográficos
Autores principales: Cui, Yun, Sun, Yin, Hu, Shuai, Luo, Jie, Li, Lei, Li, Xin, Yeh, Shuyuan, Jin, Jie, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198573/
https://www.ncbi.nlm.nih.gov/pubmed/27375022
http://dx.doi.org/10.1038/onc.2016.135

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