A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival

Ovarian cancer is a deadly disease characterized by primary and acquired resistance to chemotherapy. We previously associated NF-κB signaling with poor survival in ovarian cancer, and functionally demonstrated this pathway as mediating proliferation, invasion and metastasis. We aimed to identify coo...

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Detalles Bibliográficos
Autores principales: Hernandez, L, Kim, M K, Noonan, A M, Sagher, E, Kohlhammer, H, Wright, G, Lyle, L T, Steeg, P S, Anver, M, Bowtell, D D, Annunziata, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198842/
https://www.ncbi.nlm.nih.gov/pubmed/28179987
http://dx.doi.org/10.1038/cddiscovery.2015.53

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