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Menadione (vitamin K) enhances the antibiotic activity of drugs by cell membrane permeabilization mechanism
Menadione, vitamin K3, belongs to the class of lipid-soluble vitamins and lipophilic substances as menadione cause disturbances in the bacterial membrane, resulting in damage to the fundamental elements for the integrity of the membrane, thus allowing increased permeability. Accordingly, the aim of...
Autores principales: | Andrade, Jacqueline C., Morais Braga, Maria Flaviana B., Guedes, Gláucia Morgana M., Tintino, Saulo R., Freitas, Maria A., Quintans, Lucindo J., Menezes, Irwin R.A., Coutinho, Henrique D.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198922/ https://www.ncbi.nlm.nih.gov/pubmed/28053572 http://dx.doi.org/10.1016/j.sjbs.2015.09.004 |
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