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Phase I trial of GBS‐01 for advanced pancreatic cancer refractory to gemcitabine

GBS‐01, an extract from the fruit of Arctium lappa L. is an orally administered drug rich in arctigenin, which has been reported to exert antitumor activity by attenuating the tolerance of cancer cells to glucose deprivation. We investigated the maximum tolerated dose of GBS‐01 based on the frequenc...

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Detalles Bibliográficos
Autores principales: Ikeda, Masafumi, Sato, Akihiro, Mochizuki, Nobuo, Toyosaki, Kayo, Miyoshi, Chika, Fujioka, Rumi, Mitsunaga, Shuichi, Ohno, Izumi, Hashimoto, Yusuke, Takahashi, Hideaki, Hasegawa, Hiromi, Nomura, Shogo, Takahashi, Ryuji, Yomoda, Satoshi, Tsuchihara, Katsuya, Kishino, Satoshi, Esumi, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198948/
https://www.ncbi.nlm.nih.gov/pubmed/27685612
http://dx.doi.org/10.1111/cas.13086