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Phase I trial of GBS‐01 for advanced pancreatic cancer refractory to gemcitabine
GBS‐01, an extract from the fruit of Arctium lappa L. is an orally administered drug rich in arctigenin, which has been reported to exert antitumor activity by attenuating the tolerance of cancer cells to glucose deprivation. We investigated the maximum tolerated dose of GBS‐01 based on the frequenc...
Autores principales: | Ikeda, Masafumi, Sato, Akihiro, Mochizuki, Nobuo, Toyosaki, Kayo, Miyoshi, Chika, Fujioka, Rumi, Mitsunaga, Shuichi, Ohno, Izumi, Hashimoto, Yusuke, Takahashi, Hideaki, Hasegawa, Hiromi, Nomura, Shogo, Takahashi, Ryuji, Yomoda, Satoshi, Tsuchihara, Katsuya, Kishino, Satoshi, Esumi, Hiroyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198948/ https://www.ncbi.nlm.nih.gov/pubmed/27685612 http://dx.doi.org/10.1111/cas.13086 |
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