MiR‐133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle‐splicer polypyrimidine tract‐binding protein 1

The metabolism in tumor cells shifts from oxidative phosphorylation to glycolysis even in an aerobic environment. This phenomenon is known as the Warburg effect. This effect is regulated mainly by polypyrimidine tract‐binding protein 1 (PTBP1), which is a splicer of the mRNA for the rate‐limiting en...

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Detalles Bibliográficos
Autores principales: Sugiyama, Taro, Taniguchi, Kohei, Matsuhashi, Nobuhisa, Tajirika, Toshihiro, Futamura, Manabu, Takai, Tomoaki, Akao, Yukihiro, Yoshida, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198967/
https://www.ncbi.nlm.nih.gov/pubmed/27696637
http://dx.doi.org/10.1111/cas.13091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198967/
https://www.ncbi.nlm.nih.gov/pubmed/27696637
http://dx.doi.org/10.1111/cas.13091

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