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MiR‐133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle‐splicer polypyrimidine tract‐binding protein 1
The metabolism in tumor cells shifts from oxidative phosphorylation to glycolysis even in an aerobic environment. This phenomenon is known as the Warburg effect. This effect is regulated mainly by polypyrimidine tract‐binding protein 1 (PTBP1), which is a splicer of the mRNA for the rate‐limiting en...
Autores principales: | Sugiyama, Taro, Taniguchi, Kohei, Matsuhashi, Nobuhisa, Tajirika, Toshihiro, Futamura, Manabu, Takai, Tomoaki, Akao, Yukihiro, Yoshida, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198967/ https://www.ncbi.nlm.nih.gov/pubmed/27696637 http://dx.doi.org/10.1111/cas.13091 |
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