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Phase I study of nintedanib in Japanese patients with advanced hepatocellular carcinoma and liver impairment

This phase I, dose‐escalation study evaluated the safety, preliminary efficacy and pharmacokinetics of nintedanib, a triple angiokinase inhibitor, in Japanese patients with advanced hepatocellular carcinoma and mild/moderate liver impairment. Thirty patients with unresectable hepatocellular carcinom...

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Detalles Bibliográficos
Autores principales:	Okusaka, Takuji, Otsuka, Taiga, Ueno, Hideki, Mitsunaga, Shuichi, Sugimoto, Rie, Muro, Kei, Saito, Isao, Tadayasu, Yusuke, Inoue, Kohei, Loembé, Arsene‐Bienvenu, Ikeda, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198968/ https://www.ncbi.nlm.nih.gov/pubmed/27627050 http://dx.doi.org/10.1111/cas.13077

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