Yeast GPCR signaling reflects the fraction of occupied receptors, not the number

According to receptor theory, the effect of a ligand depends on the amount of agonist–receptor complex. Therefore, changes in receptor abundance should have quantitative effects. However, the response to pheromone in Saccharomyces cerevisiae is robust (unaltered) to increases or reductions in the ab...

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Detalles Bibliográficos
Autores principales: Bush, Alan, Vasen, Gustavo, Constantinou, Andreas, Dunayevich, Paula, Patop, Inés Lucía, Blaustein, Matías, Colman‐Lerner, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199120/
https://www.ncbi.nlm.nih.gov/pubmed/28034910
http://dx.doi.org/10.15252/msb.20166910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199120/
https://www.ncbi.nlm.nih.gov/pubmed/28034910
http://dx.doi.org/10.15252/msb.20166910

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