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Yeast GPCR signaling reflects the fraction of occupied receptors, not the number
According to receptor theory, the effect of a ligand depends on the amount of agonist–receptor complex. Therefore, changes in receptor abundance should have quantitative effects. However, the response to pheromone in Saccharomyces cerevisiae is robust (unaltered) to increases or reductions in the ab...
Autores principales: | Bush, Alan, Vasen, Gustavo, Constantinou, Andreas, Dunayevich, Paula, Patop, Inés Lucía, Blaustein, Matías, Colman‐Lerner, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199120/ https://www.ncbi.nlm.nih.gov/pubmed/28034910 http://dx.doi.org/10.15252/msb.20166910 |
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