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Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of Huntington's disease

The subthalamic nucleus (STN) is an element of cortico-basal ganglia-thalamo-cortical circuitry critical for action suppression. In Huntington's disease (HD) action suppression is impaired, resembling the effects of STN lesioning or inactivation. To explore this potential linkage, the STN was s...

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Detalles Bibliográficos
Autores principales:	Atherton, Jeremy F, McIver, Eileen L, Mullen, Matthew RM, Wokosin, David L, Surmeier, D James, Bevan, Mark D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199195/ https://www.ncbi.nlm.nih.gov/pubmed/27995895 http://dx.doi.org/10.7554/eLife.21616

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