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A Cascade of Thermophilic Enzymes As an Approach to the Synthesis of Modified Nucleotides
We propose a new approach for the synthesis of biologically important nucleotides which includes a multi-enzymatic cascade conversion of D-pentoses into purine nucleotides. The approach exploits nucleic acid exchange enzymes from thermophilic microorganisms: ribokinase, phosphoribosylpyrophosphate s...
Autores principales: | Esipov, R. S., Abramchik, Yu. A., Fateev, I. V., Konstantinova, I. D., Kostromina, M. A., Muravyova, T. I., Artemova, K. G., Miroshnikov, A. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199209/ https://www.ncbi.nlm.nih.gov/pubmed/28050269 |
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