novoBreak: local assembly for breakpoint detection in cancer genomes

We present novoBreak, a novel genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole genome sequencing data. In the ICGC-TCGA DREAM 8.5 Somatic Mutation Calling Challenge and real cancer genome data analysis, novoBreak consistently outperfo...

Descripción completa

Detalles Bibliográficos
Autores principales: Chong, Zechen, Ruan, Jue, Gao, Min, Zhou, Wanding, Chen, Tenghui, Fan, Xian, Ding, Li, Lee, Anna Y., Boutros, Paul, Chen, Junjie, Chen, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199621/
https://www.ncbi.nlm.nih.gov/pubmed/27892959
http://dx.doi.org/10.1038/nmeth.4084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199621/
https://www.ncbi.nlm.nih.gov/pubmed/27892959
http://dx.doi.org/10.1038/nmeth.4084

Ejemplares similares