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VEGF regulates local inhibitory complement proteins in the eye and kidney
Outer retinal and renal glomerular functions rely on specialized vasculature maintained by VEGF that is produced by neighboring epithelial cells, the retinal pigment epithelium (RPE) and podocytes, respectively. Dysregulation of RPE- and podocyte-derived VEGF is associated with neovascularization in...
Autores principales: | Keir, Lindsay S., Firth, Rachel, Aponik, Lyndsey, Feitelberg, Daniel, Sakimoto, Susumu, Aguilar, Edith, Welsh, Gavin I., Richards, Anna, Usui, Yoshihiko, Satchell, Simon C., Kuzmuk, Valeryia, Coward, Richard J., Goult, Jonathan, Bull, Katherine R., Sharma, Ruchi, Bharti, Kapil, Westenskow, Peter D., Michael, Iacovos P., Saleem, Moin A., Friedlander, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199702/ https://www.ncbi.nlm.nih.gov/pubmed/27918307 http://dx.doi.org/10.1172/JCI86418 |
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