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The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C

OBJECTIVES: To evaluate the effect of adjuvant intracameral triamcinolone acetonide (TA) on the surgical results of trabeculectomy with mitomycin C. MATERIALS AND METHODS: All consecutive trabeculectomy cases performed in the glaucoma clinic between July 2012 and December 2013 were retrospectively r...

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Autores principales: Alagöz, Neşe, Alagöz, Cengiz, Yıldırım, Yusuf, Yeşilkaya, Ceren, Altan, Çiğdem, Bozkurt, Ercüment, Şatana, Banu, Başarır, Berna, Taşkapılı, Muhittin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200822/
https://www.ncbi.nlm.nih.gov/pubmed/28058152
http://dx.doi.org/10.4274/tjo.88785
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author Alagöz, Neşe
Alagöz, Cengiz
Yıldırım, Yusuf
Yeşilkaya, Ceren
Altan, Çiğdem
Bozkurt, Ercüment
Şatana, Banu
Başarır, Berna
Taşkapılı, Muhittin
author_facet Alagöz, Neşe
Alagöz, Cengiz
Yıldırım, Yusuf
Yeşilkaya, Ceren
Altan, Çiğdem
Bozkurt, Ercüment
Şatana, Banu
Başarır, Berna
Taşkapılı, Muhittin
author_sort Alagöz, Neşe
collection PubMed
description OBJECTIVES: To evaluate the effect of adjuvant intracameral triamcinolone acetonide (TA) on the surgical results of trabeculectomy with mitomycin C. MATERIALS AND METHODS: All consecutive trabeculectomy cases performed in the glaucoma clinic between July 2012 and December 2013 were retrospectively reviewed from the patient charts. Only those with follow-up of 12 months or longer were included. Patients with intraoperative intracameral TA (study group, n=19) were compared to those without TA (control group, n=21) in terms of surgical success, intraocular pressure (IOP) change, medication use and complications. RESULTS: Forty eyes of 31 patients (21 male/10 female, mean age 64.2±13.8 years) were included in the study. The mean follow-up period was 20.9±5.1 months and 20.7±6.7 months in the study and control groups, respectively (p=0.830). Baseline IOP was 26.4±9.9 and 25.2±7.6 mmHg (p=0.979), and final IOP was 12.7±2.6 and 13.6±3 mmHg in both groups respectively (p=0.226). At the final follow-up, complete success was observed in 68.4% and 52.4% of the study and control groups (p=0.349) and anti-glaucoma medication was used by 31.6% (mean number of medications: 0.79±1.2) and 47.6% (mean number of medications: 1.33±1.7), respectively (p>0.05). Bleb encapsulation, leakage, suture-lysis and hypotony rates were similar in both groups (for all, p>0.05). Cataract progression was noted in six (35.3%) and in five (26.3%) of the phakic eyes in the study and control groups, respectively (p=0.720). CONCLUSION: When used intracamerally, TA did not increase the complication rate in trabeculectomy surgery. Although the group that received TA showed lower IOP levels, use of fewer medications and fewer eyes requiring medication, the differences did not reach significance.
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spelling pubmed-52008222017-01-05 The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C Alagöz, Neşe Alagöz, Cengiz Yıldırım, Yusuf Yeşilkaya, Ceren Altan, Çiğdem Bozkurt, Ercüment Şatana, Banu Başarır, Berna Taşkapılı, Muhittin Turk J Ophthalmol Original Article OBJECTIVES: To evaluate the effect of adjuvant intracameral triamcinolone acetonide (TA) on the surgical results of trabeculectomy with mitomycin C. MATERIALS AND METHODS: All consecutive trabeculectomy cases performed in the glaucoma clinic between July 2012 and December 2013 were retrospectively reviewed from the patient charts. Only those with follow-up of 12 months or longer were included. Patients with intraoperative intracameral TA (study group, n=19) were compared to those without TA (control group, n=21) in terms of surgical success, intraocular pressure (IOP) change, medication use and complications. RESULTS: Forty eyes of 31 patients (21 male/10 female, mean age 64.2±13.8 years) were included in the study. The mean follow-up period was 20.9±5.1 months and 20.7±6.7 months in the study and control groups, respectively (p=0.830). Baseline IOP was 26.4±9.9 and 25.2±7.6 mmHg (p=0.979), and final IOP was 12.7±2.6 and 13.6±3 mmHg in both groups respectively (p=0.226). At the final follow-up, complete success was observed in 68.4% and 52.4% of the study and control groups (p=0.349) and anti-glaucoma medication was used by 31.6% (mean number of medications: 0.79±1.2) and 47.6% (mean number of medications: 1.33±1.7), respectively (p>0.05). Bleb encapsulation, leakage, suture-lysis and hypotony rates were similar in both groups (for all, p>0.05). Cataract progression was noted in six (35.3%) and in five (26.3%) of the phakic eyes in the study and control groups, respectively (p=0.720). CONCLUSION: When used intracamerally, TA did not increase the complication rate in trabeculectomy surgery. Although the group that received TA showed lower IOP levels, use of fewer medications and fewer eyes requiring medication, the differences did not reach significance. Galenos Publishing 2016-08 2016-08-15 /pmc/articles/PMC5200822/ /pubmed/28058152 http://dx.doi.org/10.4274/tjo.88785 Text en ©Turkish Journal of Ophthalmology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Alagöz, Neşe
Alagöz, Cengiz
Yıldırım, Yusuf
Yeşilkaya, Ceren
Altan, Çiğdem
Bozkurt, Ercüment
Şatana, Banu
Başarır, Berna
Taşkapılı, Muhittin
The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
title The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
title_full The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
title_fullStr The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
title_full_unstemmed The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
title_short The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
title_sort effect of adjuvant intracameral triamcinolone acetonide on the surgical results of trabeculectomy with mitomycin c
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200822/
https://www.ncbi.nlm.nih.gov/pubmed/28058152
http://dx.doi.org/10.4274/tjo.88785
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