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Helicobacter pylori VacA, acting through receptor protein tyrosine phosphatase α, is crucial for CagA phosphorylation in human duodenum carcinoma cell line AZ-521
Helicobacter pylori, a major cause of gastroduodenal diseases, produces vacuolating cytotoxin (VacA) and cytotoxin-associated gene A (CagA), which seem to be involved in virulence. VacA exhibits pleiotropic actions in gastroduodenal disorders via its specific receptors. Recently, we found that VacA...
Autores principales: | Nakano, Masayuki, Yahiro, Kinnosuke, Yamasaki, Eiki, Kurazono, Hisao, Akada, Junko, Yamaoka, Yoshio, Niidome, Takuro, Hatakeyama, Masanori, Suzuki, Hidekazu, Yamamoto, Taro, Moss, Joel, Isomoto, Hajime, Hirayama, Toshiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200893/ https://www.ncbi.nlm.nih.gov/pubmed/27935824 http://dx.doi.org/10.1242/dmm.025361 |
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