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BMP4 acts as a dorsal telencephalic morphogen in a mouse embryonic stem cell culture system

The concept of a morphogen – a molecule that specifies two or more cell fates in a concentration-dependent manner – is paradigmatic in developmental biology. Much remains unknown, however, about the existence of morphogens in the developing vertebrate central nervous system (CNS), including the mous...

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Detalles Bibliográficos
Autores principales: Watanabe, Momoko, Fung, Ernest S., Chan, Felicia B., Wong, Jessica S., Coutts, Margaret, Monuki, Edwin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200901/
https://www.ncbi.nlm.nih.gov/pubmed/27815243
http://dx.doi.org/10.1242/bio.012021