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T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes Patients

Type 1 diabetes mellitus (T1D) is an immune-mediated disease. The autoreactive T cells in T1D patients attack and destroy their own pancreatic cells. In order to systematically investigate the potential autoreactive T cell receptors (TCRs), we used a high-throughput immune repertoire sequencing tech...

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Detalles Bibliográficos
Autores principales:	Tong, Yin, Li, Zhoufang, Zhang, Hua, Xia, Ligang, Zhang, Meng, Xu, Ying, Wang, Zhanhui, Deem, Michael W., Sun, Xiaojuan, He, Jiankui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200939/ https://www.ncbi.nlm.nih.gov/pubmed/28024918 http://dx.doi.org/10.1016/j.gpb.2016.10.003

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