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Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism

The translation elongation factor eEF1A is one of the most abundant proteins found within cells, and its role within protein synthesis is well documented. Levels of eEF1A are tightly controlled, with inappropriate expression linked to oncogenesis. However, the mechanisms by which increased eEF1A exp...

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Detalles Bibliográficos
Autores principales: Tarrant, Daniel J., Stirpe, Mariarita, Rowe, Michelle, Howard, Mark J., von der Haar, Tobias, Gourlay, Campbell W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201016/
https://www.ncbi.nlm.nih.gov/pubmed/27807005
http://dx.doi.org/10.1242/jcs.192831