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Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire

BACKGROUND: Clinical pharmacy activities in a pediatric inpatient department help to improve the management of patients clinically and economically. OBJECTIVE: To assess the relevance of pharmaceutical interventions (PIs) in a pediatric inpatient department in Abidjan (Cote d’Ivoire). MATERIALS AND...

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Autores principales: Abrogoua, Danho Pascal, Békégnran, César Pacôme, Gro, Bi Marius, Doffou, Elisée, Folquet, Madeleine Amorissani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201058/
https://www.ncbi.nlm.nih.gov/pubmed/28104969
http://dx.doi.org/10.4103/0976-0105.195083
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author Abrogoua, Danho Pascal
Békégnran, César Pacôme
Gro, Bi Marius
Doffou, Elisée
Folquet, Madeleine Amorissani
author_facet Abrogoua, Danho Pascal
Békégnran, César Pacôme
Gro, Bi Marius
Doffou, Elisée
Folquet, Madeleine Amorissani
author_sort Abrogoua, Danho Pascal
collection PubMed
description BACKGROUND: Clinical pharmacy activities in a pediatric inpatient department help to improve the management of patients clinically and economically. OBJECTIVE: To assess the relevance of pharmaceutical interventions (PIs) in a pediatric inpatient department in Abidjan (Cote d’Ivoire). MATERIALS AND METHODS: We carried out a cross-sectional, descriptive study from February to September 2014. The information collected was classified according to the classification of drug-related problems (DRPs) and PIs of the French Society of Clinical Pharmacy. The score assigned to each PI varied from PI(0) (without direct clinical impact) to PI(3) (vital clinical impact) as the importance of the potential clinical impact of the DRP was correlated to the severity of clinical consequences avoided by the PI. The relevance of PIs was assessed by their rate of acceptance by physicians and by the analysis of their clinical impact. RESULTS: A total of 116 PIs were performed with 31% performed during medical rounds, 68.1% during patients’ records analysis, and 0.1% on patient's admission. The main DRPs were related to noncompliance with recommendations (24.1%), overdose (21.1%), and underdosing (13.8%). The most important PIs were dose adjustment (31.8%), accuracy of drugs administration modalities (29.3%), and proposals of therapeutic choice (27.6%). The acceptance rate of PIs was highly significant (94.8%). The majority of PIs (67.3%) was assessed as having a significant clinical impact (PI(1)) and 16.4% of PIs as very significant clinical impact (PI(2)). A single PI (0.9%) was found with vital clinical impact. CONCLUSION: PIs performed were relevant and contributed to the therapeutic optimization and the prevention of iatrogenic events in pediatric inpatients.
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spelling pubmed-52010582017-01-19 Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire Abrogoua, Danho Pascal Békégnran, César Pacôme Gro, Bi Marius Doffou, Elisée Folquet, Madeleine Amorissani J Basic Clin Pharm Original Article BACKGROUND: Clinical pharmacy activities in a pediatric inpatient department help to improve the management of patients clinically and economically. OBJECTIVE: To assess the relevance of pharmaceutical interventions (PIs) in a pediatric inpatient department in Abidjan (Cote d’Ivoire). MATERIALS AND METHODS: We carried out a cross-sectional, descriptive study from February to September 2014. The information collected was classified according to the classification of drug-related problems (DRPs) and PIs of the French Society of Clinical Pharmacy. The score assigned to each PI varied from PI(0) (without direct clinical impact) to PI(3) (vital clinical impact) as the importance of the potential clinical impact of the DRP was correlated to the severity of clinical consequences avoided by the PI. The relevance of PIs was assessed by their rate of acceptance by physicians and by the analysis of their clinical impact. RESULTS: A total of 116 PIs were performed with 31% performed during medical rounds, 68.1% during patients’ records analysis, and 0.1% on patient's admission. The main DRPs were related to noncompliance with recommendations (24.1%), overdose (21.1%), and underdosing (13.8%). The most important PIs were dose adjustment (31.8%), accuracy of drugs administration modalities (29.3%), and proposals of therapeutic choice (27.6%). The acceptance rate of PIs was highly significant (94.8%). The majority of PIs (67.3%) was assessed as having a significant clinical impact (PI(1)) and 16.4% of PIs as very significant clinical impact (PI(2)). A single PI (0.9%) was found with vital clinical impact. CONCLUSION: PIs performed were relevant and contributed to the therapeutic optimization and the prevention of iatrogenic events in pediatric inpatients. Medknow Publications & Media Pvt Ltd 2016-12 /pmc/articles/PMC5201058/ /pubmed/28104969 http://dx.doi.org/10.4103/0976-0105.195083 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Abrogoua, Danho Pascal
Békégnran, César Pacôme
Gro, Bi Marius
Doffou, Elisée
Folquet, Madeleine Amorissani
Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire
title Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire
title_full Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire
title_fullStr Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire
title_full_unstemmed Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire
title_short Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D’ivoire
title_sort assessment of a clinical pharmacy activity in a pediatric inpatient department in cote d’ivoire
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201058/
https://www.ncbi.nlm.nih.gov/pubmed/28104969
http://dx.doi.org/10.4103/0976-0105.195083
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