Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non–Specificity, and Inhibition

The single–strand–specific S1 nuclease from Aspergillus oryzae is an archetypal enzyme of the S1–P1 family of nucleases with a widespread use for biochemical analyses of nucleic acids. We present the first X–ray structure of this nuclease along with a thorough analysis of the reaction and inhibition...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovaľ, Tomáš, Østergaard, Lars H., Lehmbeck, Jan, Nørgaard, Allan, Lipovová, Petra, Dušková, Jarmila, Skálová, Tereza, Trundová, Mária, Kolenko, Petr, Fejfarová, Karla, Stránský, Jan, Švecová, Leona, Hašek, Jindřich, Dohnálek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201275/
https://www.ncbi.nlm.nih.gov/pubmed/28036383
http://dx.doi.org/10.1371/journal.pone.0168832

Ejemplares similares

Ejemplares similares