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Brown Algae Polyphenol, a Prolyl Isomerase Pin1 Inhibitor, Prevents Obesity by Inhibiting the Differentiation of Stem Cells into Adipocytes
BACKGROUND: While screening for an inhibitor of the peptidyl prolyl cis/trans isomerase, Pin1, we came across a brown algae polyphenol that blocks the differentiation of fibroblasts into adipocytes. However, its effectiveness on the accumulation of fat in the body has never been studied. METHODOLOGY...
Autores principales: | Suzuki, Atsuko, Saeki, Toshiyuki, Ikuji, Hiroko, Uchida, Chiyoko, Uchida, Takafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201290/ https://www.ncbi.nlm.nih.gov/pubmed/28036348 http://dx.doi.org/10.1371/journal.pone.0168830 |
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