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Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children

The overall objective of this research was to study children’s respiratory illness levels in Targoviste (Romania) in relationship to the outdoor concentrations of airborne particulate matter with an aerodynamic diameter below 2.5 µm (PM(2.5)). We monitored and analysed the PM(2.5) concentrations acc...

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Autores principales: Dunea, Daniel, Iordache, Stefania, Pohoata, Alin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201387/
https://www.ncbi.nlm.nih.gov/pubmed/27983715
http://dx.doi.org/10.3390/ijerph13121246
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author Dunea, Daniel
Iordache, Stefania
Pohoata, Alin
author_facet Dunea, Daniel
Iordache, Stefania
Pohoata, Alin
author_sort Dunea, Daniel
collection PubMed
description The overall objective of this research was to study children’s respiratory illness levels in Targoviste (Romania) in relationship to the outdoor concentrations of airborne particulate matter with an aerodynamic diameter below 2.5 µm (PM(2.5)). We monitored and analysed the PM(2.5) concentrations according to a complex experimental protocol. The health trial was conducted over three months (October–December 2015) and required the active cooperation of the children’s parents to monitor carefully the respiratory symptoms of the child, i.e., coughing, rhinorrhoea, wheezing, and fever, as well as their outdoor program. We selected the most sensitive children (n = 25; age: 2–10 years) with perturbed respiratory health, i.e., wheezing, asthma, and associated symptoms. The estimated average PM(2.5) doses were 0.8–14.5 µg·day(−1) for weekdays, and 0.4–6.6 µg·day(−1) for the weekend. The frequency and duration of the symptoms decreased with increasing age. The 4- to 5-year old children recorded the longest duration of symptoms, except for rhinorrhoea, which suggested that this age interval is the most vulnerable to exogenous trigger agents (p < 0.01) compared to the other age groups. PM(2.5) air pollution was found to have a direct positive correlation with the number of wheezing episodes (r = 0.87; p < 0.01) in November 2015. Monitoring of wheezing occurrences in the absence of fever can provide a reliable assessment of the air pollution effect on the exacerbation of asthma and respiratory disorders in sensitive children.
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spelling pubmed-52013872016-12-30 Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children Dunea, Daniel Iordache, Stefania Pohoata, Alin Int J Environ Res Public Health Article The overall objective of this research was to study children’s respiratory illness levels in Targoviste (Romania) in relationship to the outdoor concentrations of airborne particulate matter with an aerodynamic diameter below 2.5 µm (PM(2.5)). We monitored and analysed the PM(2.5) concentrations according to a complex experimental protocol. The health trial was conducted over three months (October–December 2015) and required the active cooperation of the children’s parents to monitor carefully the respiratory symptoms of the child, i.e., coughing, rhinorrhoea, wheezing, and fever, as well as their outdoor program. We selected the most sensitive children (n = 25; age: 2–10 years) with perturbed respiratory health, i.e., wheezing, asthma, and associated symptoms. The estimated average PM(2.5) doses were 0.8–14.5 µg·day(−1) for weekdays, and 0.4–6.6 µg·day(−1) for the weekend. The frequency and duration of the symptoms decreased with increasing age. The 4- to 5-year old children recorded the longest duration of symptoms, except for rhinorrhoea, which suggested that this age interval is the most vulnerable to exogenous trigger agents (p < 0.01) compared to the other age groups. PM(2.5) air pollution was found to have a direct positive correlation with the number of wheezing episodes (r = 0.87; p < 0.01) in November 2015. Monitoring of wheezing occurrences in the absence of fever can provide a reliable assessment of the air pollution effect on the exacerbation of asthma and respiratory disorders in sensitive children. MDPI 2016-12-15 2016-12 /pmc/articles/PMC5201387/ /pubmed/27983715 http://dx.doi.org/10.3390/ijerph13121246 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dunea, Daniel
Iordache, Stefania
Pohoata, Alin
Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children
title Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children
title_full Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children
title_fullStr Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children
title_full_unstemmed Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children
title_short Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children
title_sort fine particulate matter in urban environments: a trigger of respiratory symptoms in sensitive children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201387/
https://www.ncbi.nlm.nih.gov/pubmed/27983715
http://dx.doi.org/10.3390/ijerph13121246
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