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Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model

The IL-2/IL-2Ralpha (CD25) axis is of central importance for the interplay of effector and regulatory T cells. Nevertheless, the question how different antigen loads are translated into appropriate IL-2 production to ensure adequate responses against pathogens remains largely unexplored. Here we fin...

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Detalles Bibliográficos
Autores principales:	Fuhrmann, Franziska, Lischke, Timo, Gross, Fridolin, Scheel, Tobias, Bauer, Laura, Kalim, Khalid Wasim, Radbruch, Andreas, Herzel, Hanspeter, Hutloff, Andreas, Baumgrass, Ria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201416/ https://www.ncbi.nlm.nih.gov/pubmed/28035902 http://dx.doi.org/10.7554/eLife.20616

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